Total synthesis of cananginone C and structural revision of debilisone A.
نویسندگان
چکیده
A short, convergent and general strategy for stereoselective total synthesis of biologically active α-substituted γ-hydroxymethyl γ-lactone based natural products cananginone C and debilisone A has been developed. The salient features of this synthesis include Cadiot-Chodkiewicz coupling, Evans allylation, Sharpless asymmetric dihydroxylation and γ-lactonization. The originally proposed structure of debilisone A has been revised.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 14 37 شماره
صفحات -
تاریخ انتشار 2016